akuamma seeds

Akuamma Seeds: Everything You Need To Know

Akuamma Seeds: an introduction:

Akuamma is a plant that is found in different parts of Africa, especially in the Ivory Coast, Nigeria, and Ghana. The seeds of this plant are dried, grounded, and powdered for use in various ailments. Akuamma has been used by the natives in treating malaria, and diarrhea.

They are used as anti-inflammatory, painkiller, antipyretic, and anti-diabetic. Akuamma is effective is treating African Trypanosomiasis, which is a parasitic disease. The disease is named as ‘sleeping sickness’ because it has the ability to provide a disturbed sleeping pattern. Let’s get to know more about it in this article.

Akuamma seeds: An alternative to kratom

The different types of alkaloids present in the Akuamma seeds help in providing a huge array of healing qualities. The Akuamma seeds are compared to kratom because the akuammine present in the seeds is relatable to mitragynine, and yohimbine.

The alkaloid akuammine is believed to stimulate glucose uptake. That’s the reason why this seed is being used traditionally in maintaining diabetes mellitus, which is famous in Nigeria. A hospital in Ghana started to develop 250 mg capsules of the Akuamma seeds in powdered form.

The powder is named as ‘Picap’, and it became widely famous as a safe and natural pain-relieving medication. Afterward, many studies were conducted to unearth the potentialities of the active alkaloids present in Akuamma.

Alkaloids present in the Akuamma seeds:

The alkaloids present in Akuamma are divided into two groups, and they are akuammine and pericine. The former one affects the opioid binding receptors, such as the kappa, delta, and mu. The effects of pericine are still to be discovered, but there are huge chances that they might provide different health properties. Here are the alkaloids that are present in Akuamma seeds.

Akuammidine – The main alkaloid content in the seeds is the Akuammidine, which comprises about 0.56% of the total amount of dried powder. It is pretty much similar to yohimbine and mitragynine. Akuammidine influences the opioid receptors like the kappa, delta, and mu. This particular alkaloid exhibits hypotensive, local analgesic activities, and skeletal muscle relaxant. In reality, the local analgesic qualities can be potent as three times as codeine.

Pseudoakuammigine – This type of alkaloid has the ability to provide anti-inflammatory and analgesic properties. When the seeds are taken in higher doses, it regulates the central nervous system, smooths the muscle contraction, respiration, and skeletal muscle contraction.  And, when it is used at a lower dosage, it gives the feeling of excitement. It also provides hypotensive, and analgesic properties.

Akuammine – This kind of alkaloid shows higher bonding for the mu receptors, unlike the Akuammidine. The alkaloid has a high potency analgesic activity, which can be compared with the effects of cocaine. When it is taken at high doses, it might cause the slow-down of the muscular contraction movement on the intestines. It can also generate hypertensive impact, but weaker than yohimbine.

Akuammigine – Although the alkaloid showed very little or no effects when conducted on one opioid test, this alkaloid is reported to have an anti-adrenergic effect on the blood vessels, and heart. It also causes an impact on the regulatory center present in the circulation system of the body.

Akuammicine – This particular alkaloid shows its highest bondage with the kappa opioid receptors in the central nervous system.

Pericine – The alkaloid is believed to bind with the mu-opioid receptors in the nervous system, but might result in involuntary muscle contractions.

Some other forms of alkaloids present in the Akuamma seeds include Picraciine, Burnamin, Picraphylline, Desacetylakuammiline, and Picraline.

Health benefits associated with Akuamma seeds:

These days more and more people are turning to folk medicines, who are suffering from chronic ailments, for getting cured. The Akuamma seeds are used to boost energy, sexual desire, treats coughs, and helps in opiate withdrawal. Here are the positive effects of using Akuamma seeds.

Soothing and relaxing effect – Akuamma is popular for reducing anxiety and stress, by providing a relaxed mental state, and helps in attaining a calm and soothing effect. There are several users who have reported the seeds particularly come handy for them to counter panic attacks.

Pain reliever – Akuamma seeds are known for their analgesic properties. Many users have reported that the proper use of the seeds can be helpful in alleviating pain, which is caused by migraine, fibromyalgia, lupus erythematosus, and arthritis. They have reported that it is a better alternative than opiates, because it does not result in withdrawal side effects, and have very low chances of addiction.

Additionally, the seeds are naturally occurring substance and have the least chances of side effects. For fighting against pain, one or two Akuamma seeds are considered enough for the effect. People who are active or athletes can use the seeds for relaxing the sore muscles.

The effects of pain-relieving derived from the Akuamma seeds is almost immediate and it can be noticed within 20 to 30 minutes of using it. However, some users have reported that the effects are not as stronger than kratom, but it has helped them a lot.

Sedation – It is one of the widely known effects of Akuamma seeds. The powerful sedative properties of the seeds relieve an individual from various sleeping disorders that include nightmares, and insomnia. If the seeds are taken at night before going to bed, it will help in providing a great peaceful sleep. Many users of this seed have reported receiving the calming effect, which can be noticed in one hour. People who are having trouble in sleep because of stress, anxiety, and pain, can achieve great sleep.

Anti-diabetic – The alkaloids present in the Akuamma seeds are reported to have anti-diabetic properties. The alkaloid helps in the glucose uptake in the cells, and therefore reduces the glucose levels in the blood.

Anti-parasitic – The Akuamma seeds are also famous for their potency against certain parasites. They are believed to work against a specific type of parasitic protozoan, known as a Trypanosoma. This parasite can cause several diseases like African sleeping sickness, Leishmaniosis, and Chagas disease. Some studies have proved that these diseases can be cured by using seeds.

Anti-malarial – The bark, fruit, and the seeds of Akuamma are being researched for anti-malarial remedy. The two kinds of alkaloids present in them, namely akuammine and also nine, are outstanding for malarial therapy.

Side effects of Akuamma seeds:

Here are some of the adverse effects that can be found while using the seeds.

Hypernatremia and hyperkalemia – Akuamma could cause ion regulatory problems that might include increased levels of sodium and potassium in the plasma. However, the problems are not big enough for getting serious.

Headache – When there is a larger dosage of more than 2 grams of Akuamma, there are chances that you can experience a headache. Although, at higher doses, you will also get sedated.

Bitter flavor – The bad thing about Akuamma seeds is its bitter taste, which is even more horrible than kratom. There is no possibility that you can take the seeds, because you might vomit, or feel nauseous soon after taking it.

Various users have mentioned that because they are bothered by its taste, they usually grind the seeds in a blender, add some quantity of turmeric powder, and place them on capsules. That’s how they escape from the bad taste of Akuamma. You can consider adding a sweetener when you use it with tea or other drinks.


Many people use Akuamma as a pain reliever and achieved great results. It also helps in reducing stress, anxiety, and insomnia as well.